Nulliparity is associated with less healthy markers of subclinical cardiovascular disease in young women with overweight and obesity.

ABSTRACT:

Objective

Higher parity is associated with increased subclinical cardiovascular disease (CVD) in mid-life and older women and with increased CVD risk overall. The relationship between parity, subclinical CVD, and infertility in young women with overweight and obesity has been infrequently evaluated.

Methods

Reproductive histories were obtained in 191 (66%) young women with overweight and obesity (BMI 25-39.9 kg/m(2) ) participating in a weight loss trial. Baseline carotid intima-media thickness (IMT) and inter-adventitial diameter (IAD) were assessed via B-mode ultrasound. Linear regression was used to estimate the relationship between parity and carotid measures, adjusted for demographic, cardiovascular, and reproductive risk factors.

Results

Nulliparous women (n = 7

SUBMITTER: Niemczyk NA 

PROVIDER: S-EPMC4414732 | biostudies-literature | 2015 May

REPOSITORIES: biostudies-literature