Type 2 diabetes mellitus and colorectal neoplasia risk in Hispanics: a case-control study.

ABSTRACT:

Aims

There is inconclusive evidence regarding the potential link between diabetes mellitus (DM) and colorectal cancer (CRC). Associations between type 2 DM and colorectal neoplasia (CRN; colorectal cancer and/or adenomas) have not been well studied in Hispanics, an ethnic minority at high risk for type 2 DM. This study aims to assess the association between type 2 DM and CRN in Hispanics.

Methods

Hispanics with incident CRN and colonoscopy-negative controls from 2005 to 2009 were evaluated. Diagnosis of type 2 DM was established by previous medical diagnosis and/or use of DM treatments. Unconditional logistic regression was performed to estimate odds ratios for the association between type 2 DM and CRN.

Results

A total of 451 participants (mean age 61.1±11.9years, 59.

SUBMITTER: Diaz-Algorri Y 

PROVIDER: S-EPMC4414902 | biostudies-literature | 2015 May-Jun

REPOSITORIES: biostudies-literature