SDPMOD: an automated comparative modeling server for small disulfide-bonded proteins.

ABSTRACT: Small disulfide-bonded proteins (SDPs) are rich sources for therapeutic drugs. Designing drugs from these proteins requires three-dimensional structural information, which is only available for a subset of these proteins. SDPMOD addresses this deficit in structural information by providing a freely available automated comparative modeling service to the research community. For expert users, SDPMOD offers a manual mode that permits the selection of a desired template as well as a semi-automated mode that allows users to select the template from a suggested list. Besides the selection of templates, expert users can edit the target-template alignment, thus allowing further customization of the modeling process. Furthermore, the web service provides model stereochemical quality evaluation usin

SUBMITTER: Kong L 

PROVIDER: S-EPMC441532 | biostudies-literature | 2004 Jul

REPOSITORIES: biostudies-literature