FATCAT: a web server for flexible structure comparison and structure similarity searching.

ABSTRACT: Protein structure comparison, an important problem in structural biology, has two main applications: (i) comparing two protein structures in order to identify the similarities and differences between them, and (ii) searching for structures similar to a query structure. Many web-based resources for both applications are available, but all are based on rigid structural alignment algorithms. FATCAT server implements the recently developed flexible protein structure comparison algorithm FATCAT, which automatically identifies hinges and internal rearrangements in two protein structures. The server provides access to two algorithms: FATCAT-pairwise for pairwise flexible structure comparison and FATCAT-search for database searching for structurally similar proteins. Given two protein structures [

SUBMITTER: Ye Y 

PROVIDER: S-EPMC441568 | biostudies-literature | 2004 Jul

REPOSITORIES: biostudies-literature