Longitudinal changes in self-reported walking ability in multiple sclerosis.

ABSTRACT:

Background

Patient-reported outcomes are increasingly used to understand the clinical meaningfulness of multiple sclerosis disability and its treatments. For example, the 12-item Multiple Sclerosis Walking Scale (MSWS-12) measures the patient-reported impact of the disease on walking ability.

Objective

We studied longitudinal changes in walking ability using the MSWS-12 in a cohort of 108 patients with relapsing-remitting multiple sclerosis and moderate-to-severe disability from a single US center cohort study investigating multiple sclerosis symptoms and physical activity.

Methods

The MSWS-12 was completed every 6 months over 2 years together with self-reported measures of disease impact on daily life (Multiple Sclerosis Impact Scale) and walking disability (Patient

SUBMITTER: Motl RW 

PROVIDER: S-EPMC4416760 | biostudies-literature | 2015

REPOSITORIES: biostudies-literature