Costly Inheritance and the Persistence of Insecticide Resistance in Aedes aegypti Populations.

ABSTRACT: Global emergence of arboviruses is a growing public health concern, since most of these diseases have no vaccine or prevention treatment available. In this scenario, vector control through the use of chemical insecticides is one of the most important prevention tools. Nevertheless, their effectiveness has been increasingly compromised by the development of strong resistance observed in field populations, even in spite of fitness costs usually associated to resistance. Using a stage-structured deterministic model parametrised for the Aedes aegypti--the main vector for dengue--we investigated the persistence of resistance by studying the time for a population which displays resistance to insecticide to revert to a susceptible population. By means of a comprehensive series of in-silico experi

SUBMITTER: Schechtman H 

PROVIDER: S-EPMC4416794 | biostudies-literature | 2015

REPOSITORIES: biostudies-literature