SMASH - semi-automatic muscle analysis using segmentation of histology: a MATLAB application.

ABSTRACT:

Background

Histological assessment of skeletal muscle tissue is commonly applied to many areas of skeletal muscle physiological research. Histological parameters including fiber distribution, fiber type, centrally nucleated fibers, and capillary density are all frequently quantified measures of skeletal muscle. These parameters reflect functional properties of muscle and undergo adaptation in many muscle diseases and injuries. While standard operating procedures have been developed to guide analysis of many of these parameters, the software to freely, efficiently, and consistently analyze them is not readily available. In order to provide this service to the muscle research community we developed an open source MATLAB script to analyze immunofluorescent muscle sections incorporatin

SUBMITTER: Smith LR 

PROVIDER: S-EPMC4417508 | biostudies-literature | 2014

REPOSITORIES: biostudies-literature