Dataset Information

Reduced Bone Density and Vertebral Fractures in Smokers. Men and COPD Patients at Increased Risk.

ABSTRACT:

Rationale

Former smoking history and chronic obstructive pulmonary disease (COPD) are potential risk factors for osteoporosis and fractures. Under existing guidelines for osteoporosis screening, women are included but men are not, and only current smoking is considered.

Objectives

To demonstrate the impact of COPD and smoking history on the risk of osteoporosis and vertebral fracture in men and women.

Methods

Characteristics of participants with low volumetric bone mineral density (vBMD) were identified and related to COPD and other risk factors. We tested associations of sex and COPD with both vBMD and fractures adjusting for age, race, body mass index (BMI), smoking, and glucocorticoid use.