Value of Computerized 3D Shape Analysis in Differentiating Encapsulated from Invasive Thymomas.

ABSTRACT:

Objectives

To retrospectively investigate the added value of quantitative 3D shape analysis in differentiating encapsulated from invasive thymomas.

Materials and methods

From February 2002 to October 2013, 53 patients (25 men and 28 women; mean age, 53.94 ± 13.13 years) with 53 pathologically-confirmed thymomas underwent preoperative chest CT scans (slice thicknesses ≤ 2.5 mm). Twenty-three tumors were encapsulated thymomas and 30 were invasive thymomas. Their clinical and CT characteristics were evaluated. In addition, each thymoma was manually-segmented from surrounding structures, and their 3D shape features were assessed using an in-house developed software program. To evaluate the added value of 3D shape features in differentiating encapsulated from invasive thymomas, l

SUBMITTER: Lee JH 

PROVIDER: S-EPMC4418613 | biostudies-literature | 2015

REPOSITORIES: biostudies-literature