Heterogeneity of Iranian clinical isolates of Mycobacterium fortuitum.

ABSTRACT:

Background and objectives

The increase of infections caused by nontuberculous mycobacteria (NTM) is receiving increasing attention worldwide. Mycobacterium fortuitum is encountered with increasing frequency in clinical laboratories of Iran.

Materials and methods

Sequence variation of 48 M. fortuitum clinical isolates, were investigated by sequence analysis of the 16S-23S Internal Transcribed Spacer.

Results

Twelve different sequence types (sequevar) were identified by sequence analysis of ITS region. Seven previously described sequevar including MfoA, MfoB, MfoC, MfoD, MfoE, MfoF and MfoG identified. Five novel sequevar namely MfoH, MfoI, MfoJ, MfoK and MfoL that were distinctly different from the previously described sequevar were detected among different clinical st

SUBMITTER: Hashemi-Shahraki A 

PROVIDER: S-EPMC4419039 | biostudies-literature | 2014 Feb

REPOSITORIES: biostudies-literature