Merkel cell polyomavirus infection in a patient with merkel cell carcinoma: a case report.

ABSTRACT:

Introduction

Merkel cell carcinoma (MCC) is a rare and highly aggressive malignancy of the skin which occurs mainly in old people and is very uncommon in young individuals. A new tumor virus belonging to the Polyomaviridae family; Merkel Cell Polyomavirus (MCPyV) has recently been identified in more than 80% of MCCs.

Case presentation

We conducted a retrospective review on the archives of the Department of Pathology; Imam Khomeini Hospital Cancer Institute affiliated to Tehran University of Medical Sciences to confirm the MCC samples and we found medical records and samples of a young case with MCC who developed leg skin and scalp tumor six and seven years after bone marrow transplantation, respectively. We analyzed patient formalin-fixed paraffin-embedded samples for the pr

SUBMITTER: Sadeghi F 

PROVIDER: S-EPMC4419364 | biostudies-literature | 2015 Mar

REPOSITORIES: biostudies-literature