Clinical evaluation of commercial nucleic acid amplification tests in patients with suspected sepsis.

ABSTRACT:

Background

Sepsis is a serious medical condition requiring timely administered, appropriate antibiotic therapy. Blood culture is regarded as the gold standard for aetiological diagnosis of sepsis, but it suffers from low sensitivity and long turnaround time. Thus, nucleic acid amplification tests (NAATs) have emerged to shorten the time to identification of causative microbes. The aim of the present study was to evaluate the clinical utility in everyday practice in the emergency department of two commercial NAATs in patients suspected with sepsis.

Methods

During a six-week period, blood samples were collected consecutively from all adult patients admitted to the general emergency department for suspicion of a community-onset sepsis and treated with intravenous antibiotics. A

SUBMITTER: Ljungstrom L 

PROVIDER: S-EPMC4419503 | biostudies-literature | 2015 Apr

REPOSITORIES: biostudies-literature