Trajectory of body mass index before the development of type 2 diabetes in Japanese men: Toranomon Hospital Health Management Center Study 15.

ABSTRACT:

Aims/introduction

We aimed to investigate the long-term trajectory of general adiposity assessed by the body mass index (BMI) before the onset of type 2 diabetes in Japanese individuals.

Materials and methods

We retrospectively examined data on 1,553 Japanese men without diabetes. Mean BMI and incident cases of diabetes (diabetes indicated by fasting glucose concentrations ≥7.0 mmol/L, a self-reported history of clinician-diagnosed diabetes, or glycated hemoglobin ≥6.5% (≥48 mmol/mol) were assessed on an annual basis over a 10-year period after the baseline examination.

Results

Mean (standard deviation) BMI at the time of diagnosis was 24.4 kg/m(2) (3.1 kg/m(2)) among cases of diabetes (n = 191). An increasingly high BMI was associated with the early stage of the dise

SUBMITTER: Heianza Y 

PROVIDER: S-EPMC4420560 | biostudies-literature | 2015 May

REPOSITORIES: biostudies-literature