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Hypocomplementaemic immune complex tubulointerstitial nephritis.


ABSTRACT: We report a rare cause of rapidly progressive renal failure associated with low complement, positive ANA but negative anti DS-DNA. A renal biopsy demonstrated tubulointerstitial nephritis with positive immunoglobulin staining involving the interstitium and tubular basement membrane but glomerular sparing. A review of the literature and differential diagnosis are discussed.

SUBMITTER: Gupta A 

PROVIDER: S-EPMC4421536 | biostudies-literature | 2010 Feb

REPOSITORIES: biostudies-literature

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Hypocomplementaemic immune complex tubulointerstitial nephritis.

Gupta Alok A   Jothy Serge S   Somerville Peter P   Zaltzman Jeffrey S JS  

NDT plus 20091007 1


We report a rare cause of rapidly progressive renal failure associated with low complement, positive ANA but negative anti DS-DNA. A renal biopsy demonstrated tubulointerstitial nephritis with positive immunoglobulin staining involving the interstitium and tubular basement membrane but glomerular sparing. A review of the literature and differential diagnosis are discussed. ...[more]

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2022-09-24 | GSE213683 | GEO