CKD and Its Risk Factors among Patients with Cystinuria.

ABSTRACT:

Background and objectives

Cystinuria is an autosomal recessive disorder affecting renal cystine reabsorption; it causes 1% and 8% of stones in adults and children, respectively. This study aimed to determine epidemiologic and clinical characteristics as well as comorbidities among cystinuric patients, focusing on CKD and high BP.

Design, setting, participants, & measurements

This retrospective study was conducted in France, and involved 47 adult and pediatric nephrology and urology centers from April 2010 to January 2012. Data were collected from 442 cystinuric patients.

Results

Median age at onset of symptoms was 16.7 (minimum to maximum, 0.3-72.1) years and median diagnosis delay was 1.3 (0-45.7) years. Urinary alkalinization and cystine-binding thiol were prescribe

SUBMITTER: Prot-Bertoye C 

PROVIDER: S-EPMC4422236 | biostudies-literature | 2015 May

REPOSITORIES: biostudies-literature