Synthesis and bioactivities of silver nanoparticles capped with 5-amino-β-resorcylic acid hydrochloride dihydrate.

ABSTRACT:

Background

Conjugated and drug loaded silver nanoparticles are getting an increased attention for various biomedical applications. Nanoconjugates showed significant enhancement in biological activity in comparison to free drug molecules. In this perspective, we report the synthesis of bioactive silver capped with 5-Amino-β-resorcylic acid hydrochloride dihydrate (AR). The in vitro antimicrobial (antibacterial, antifungal), enzyme inhibition (xanthine oxidase, urease, carbonic anhydrase, α-chymotrypsin, cholinesterase) and antioxidant activities of the developed nanostructures was investigated before and after conjugation to silver metal.

Results

The conjugation of AR to silver was confirmed through FTIR, UV-vis and TEM techniques. The amount of AR conjugated with silver was

SUBMITTER: Naz SS 

PROVIDER: S-EPMC4422292 | biostudies-literature | 2014 Sep

REPOSITORIES: biostudies-literature