A Prognostic Model for Development of Profound Shock among Children Presenting with Dengue Shock Syndrome.

ABSTRACT:

Purpose

To identify risk factors and develop a prediction model for the development of profound and recurrent shock amongst children presenting with dengue shock syndrome (DSS).

Methods

We analyzed data from a prospective cohort of children with DSS recruited at the Paediatric Intensive Care Unit of the Hospital for Tropical Disease in Ho Chi Minh City, Vietnam. The primary endpoint was "profound DSS", defined as ≥2 recurrent shock episodes (for subjects presenting in compensated shock), or ≥1 recurrent shock episodes (for subjects presenting initially with decompensated/hypotensive shock), and/or requirement for inotropic support. Recurrent shock was evaluated as a secondary endpoint. Risk factors were pre-defined clinical and laboratory variables collected at the time of p

SUBMITTER: Lam PK 

PROVIDER: S-EPMC4422752 | biostudies-literature | 2015

REPOSITORIES: biostudies-literature