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Meter-long multiblock copolymer microfibers via interfacial bioorthogonal polymerization.


ABSTRACT: High-molecular-weight multiblock copolymers are synthesized as robust polymer fibers via interfacial bioorthogonal polymerization employing the rapid cycloaddition of s-tetrazines with strained trans-cyclooctenes. When cell-adhesive peptide is incorporated in the tetrazine monomer, the resulting protein-mimetic polymer fibers provide guidance cues for cell attachment and elongation.

SUBMITTER: Liu S 

PROVIDER: S-EPMC4423755 | biostudies-literature | 2015 May

REPOSITORIES: biostudies-literature