The central nervous system transcriptome of the weakly electric brown ghost knifefish (Apteronotus leptorhynchus): de novo assembly, annotation, and proteomics validation.

ABSTRACT:

Background

The brown ghost knifefish (Apteronotus leptorhynchus) is a weakly electric teleost fish of particular interest as a versatile model system for a variety of research areas in neuroscience and biology. The comprehensive information available on the neurophysiology and neuroanatomy of this organism has enabled significant advances in such areas as the study of the neural basis of behavior, the development of adult-born neurons in the central nervous system and their involvement in the regeneration of nervous tissue, as well as brain aging and senescence. Despite substantial scientific interest in this species, no genomic resources are currently available.

Results

Here, we report the de novo assembly and annotation of the A. leptorhynchus transcriptome. After evaluati

SUBMITTER: Salisbury JP 

PROVIDER: S-EPMC4424500 | biostudies-literature | 2015 Mar

REPOSITORIES: biostudies-literature