A randomized controlled trial of the embrace advanced scar therapy device to reduce incisional scar formation.

ABSTRACT:

Background

Scarring represents a significant biomedical burden in clinical medicine. Mechanomodulation has been linked to scarring through inflammation, but until now a systematic approach to attenuate mechanical force and reduce scarring has not been possible.

Methods

The authors conducted a 12-month, prospective, open-label, randomized, multicenter clinical trial to evaluate abdominoplasty scar appearance following postoperative treatment with the embrace Advanced Scar Therapy device to reduce mechanical forces on healing surgical incisions. Incisions from 65 healthy adult subjects were randomized to receive embrace treatment on one half of an abdominoplasty incision and control treatment (surgeon's optimal care methods) on the other half. The primary endpoint for this stu

SUBMITTER: Longaker MT 

PROVIDER: S-EPMC4425293 | biostudies-literature | 2014 Sep

REPOSITORIES: biostudies-literature