Genetic and Environmental Contributions to Covariation Between DHEA and Testosterone in Adolescent Twins.
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ABSTRACT: Although several studies have shown that pubertal tempo and timing are shaped by genetic and environmental factors, few studies consider to what extent endocrine triggers of puberty are shaped by genetic and environmental factors. Doing so moves the field from examining correlated developmentally-sensitive biomarkers toward understanding what drives those associations. Two puberty related hormones, dehydroepiandrosterone and testosterone, were assayed from salivary samples in 118 MZ (62 % female), 111 same sex DZ (46 % female) and 103 opposite-sex DZ twin pairs, aged 12-16 years (M = 13.1, SD = 1.3). Pubertal status was assessed with a composite of mother- and self-reports. We used biometric models to estimate the genetic and environmental influences on the variance and covariance in testo
SUBMITTER: Van Hulle CA
PROVIDER: S-EPMC4425578 | biostudies-literature | 2015 May
REPOSITORIES: biostudies-literature
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