Risk factors for abandonment of Wilms tumor therapy in Kenya.

ABSTRACT:

Background

Survival from Wilms tumor (WT) in sub-Saharan Africa remains dismal as a result of on-therapy mortality and treatment abandonment. Review of patients diagnosed from 2008 to 2011 in our Kenyan Wilms Tumor Registry showed a loss to follow up (LTFU) rate approaching 50%. The purpose of this study was to trace those LTFU, estimate the survival rate, and identify risk factors for treatment abandonment.

Procedure

We administered a comprehensive survey to parents of patients with WT at the two largest referral hospitals in Kenya to identify barriers to care. We also telephoned families who had abandoned care to determine vital status and identify risk factors for treatment abandonment.

Results

Of 136 registered patients, 77 were confirmed dead (56.7%), 38 remained

SUBMITTER: Libes J 

PROVIDER: S-EPMC4425627 | biostudies-literature | 2015 Feb

REPOSITORIES: biostudies-literature