P-selectin Plasma Levels and Genetic Variant Associated With Diabetic Retinopathy in African Americans.

ABSTRACT:

Purpose

To report the prevalence and risk factors for retinopathy in African Americans with impaired fasting glucose (IFG) and type 2 diabetes in the Jackson Heart Study and to determine if P-selectin plasma levels are independently associated with retinopathy in this population.

Design

Prospective, cross-sectional observational study.

Methods

setting: Community-based epidemiologic study.

Study population

Total of 629 patients with type 2 diabetes and 266 participants with impaired fasting glucose.

Observation procedures

Bilateral, 7-field fundus photographs were scored by masked readers for diabetic retinopathy (DR) level. Covariate data including P-selectin plasma levels and genotypes were collected in a standardized fashion.

Main outcome measures</

SUBMITTER: Penman A 

PROVIDER: S-EPMC4426234 | biostudies-literature | 2015 Jun

REPOSITORIES: biostudies-literature