Epinephrine use in positive oral food challenges performed as a screening test for food allergy therapy trials.

ABSTRACT:

Background

Previous studies report epinephrine use for positive oral food challenges (OFCs) to be 9-11% when generally performed to determine outgrowth of food allergies. Epinephrine use for positive OFCs performed as screening criteria for enrollment in therapeutic trials for food allergy has not been reported.

Objective

The objective of this study was to assess the characteristics and treatment for positive OFCs performed for screening subjects for food therapeutic trials.

Methods

Retrospective review of positive screening OFCs from 2 treatment trials, food allergy herbal formula-2 (n = 45) and milk oral immunotherapy (n = 29), conducted at the Icahn School of Medicine at Mount Sinai was performed.

Results

The most common initial symptom elicited was oral pru

SUBMITTER: Noone S 

PROVIDER: S-EPMC4426243 | biostudies-literature | 2015 May-Jun

REPOSITORIES: biostudies-literature