The undiagnosed chronically-infected HCV population in France. Implications for expanded testing recommendations in 2014.

ABSTRACT:

Background

Recent HCV therapeutic advances make effective screening crucial for potential HCV eradication. To identify the target population for a possible population-based screening strategy to complement current risk-based testing in France, we aimed to estimate the number of adults with undiagnosed chronic HCV infection and age and gender distribution at two time points: 2004 and 2014.

Methods

A model taking into account mortality, HCV incidence and diagnosis rates was applied to the 2004 national seroprevalence survey.

Results

In 2014, an estimated 74,102 individuals aged 18 to 80 were undiagnosed for chronic HCV infection (plausible interval: 64,920-83,283) compared with 100,868 [95%CI: 58,534-143,202] in 2004. Men aged 18-59 represented approximately half of the

SUBMITTER: Brouard C 

PROVIDER: S-EPMC4427442 | biostudies-literature | 2015

REPOSITORIES: biostudies-literature