Direct benefit of vaccinating boys along with girls against oncogenic human papillomavirus: bayesian evidence synthesis.

ABSTRACT:

Objective

To assess the reduction in the vaccine preventable burden of cancer in men if boys are vaccinated along with girls against oncogenic human papillomavirus (HPV).

Design

Bayesian evidence synthesis approach used to evaluate the impact of vaccination against HPV types 16 and 18 on the burden of anal, penile, and oropharyngeal carcinomas among heterosexual men and men who have sex with men. The reduced transmission of vaccine-type HPV from vaccination of girls was assumed to lower the risk of HPV associated cancer in all men but not to affect the excess risk of HPV associated cancers among men who have sex with men.

Setting

General population in the Netherlands.

Intervention

Inclusion of boys aged 12 into HPV vaccination programmes.

Main outcome measur

SUBMITTER: Bogaards JA 

PROVIDER: S-EPMC4428278 | biostudies-literature | 2015 May

REPOSITORIES: biostudies-literature