A systematic review of the incidence and prevalence of sleep disorders and seizure disorders in multiple sclerosis.

ABSTRACT:

Background

Several studies have suggested that comorbid neurologic disorders are more common than expected in multiple sclerosis (MS).

Objective

To estimate the incidence and prevalence of comorbid seizure disorders and sleep disorders in persons with MS and to evaluate the quality of studies included.

Methods

The PUBMED, EMBASE, Web of Knowledge, and SCOPUS databases, conference proceedings, and reference lists of retrieved articles were searched. Two reviewers independently screened abstracts to identify relevant articles, followed by full-text review of selected articles. We assessed included studies qualitatively and quantitatively (I² statistic), and conducted meta-analyses among population-based studies.

Results

We reviewed 32 studies regarding seizure di

SUBMITTER: Marrie RA 

PROVIDER: S-EPMC4429167 | biostudies-literature | 2015 Mar

REPOSITORIES: biostudies-literature