A systematic review of the incidence and prevalence of cancer in multiple sclerosis.

ABSTRACT:

Background

Studies of cancer incidence and prevalence in multiple sclerosis (MS) have produced conflicting results.

Objective

To estimate the incidence and prevalence of cancer in persons with MS and review the quality of included studies.

Methods

We searched the PUBMED, SCOPUS, Web of Knowledge, and EMBASE databases, conference proceedings, and reference lists of all articles retrieved. Abstracts were screened for relevance by two reviewers. Data from included articles were captured using a standardized form, and the abstraction was verified by a second reviewer. We assessed quality of the included studies. We quantitatively assessed studies using the I (2) statistic, and conducted meta-analyses for population-based studies.

Results

We identified 38 studies. E

SUBMITTER: Marrie RA 

PROVIDER: S-EPMC4429168 | biostudies-literature | 2015 Mar

REPOSITORIES: biostudies-literature