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Sex peptide receptor is required for the release of stored sperm by mated Drosophila melanogaster females.


ABSTRACT: The storage of sperm in mated females is important for efficient reproduction. After sperm are transferred to females during mating, they need to reach and enter into the site(s) of storage, be maintained viably within storage, and ultimately be released from storage to fertilize eggs. Perturbation of these events can have drastic consequences on fertility. In Drosophila melanogaster, females store sperm for up to 2 weeks after a single mating. For sperm to be released normally from storage, Drosophila females need to receive the seminal fluid protein (SFP) sex peptide (SP) during mating. SP, which binds to sperm in storage, signals through the sex peptide receptor (SPR) to elicit two other effects on mated females: the persistence of egg laying and a reduction in sexual receptivity. Howev

SUBMITTER: Avila FW 

PROVIDER: S-EPMC4430431 | biostudies-literature | 2015 May

REPOSITORIES: biostudies-literature