Disproportionate fetal growth and the risk for congenital cerebral palsy in singleton births.

ABSTRACT:

Objective

To investigate the association between proportionality of fetal and placental growth measured at birth and the risk for congenital cerebral palsy (CP).

Study design

We identified all live-born singletons born in Denmark between 1995 and 2003 and followed them from 1 year of age until December 31st, 2008. Information on four indices of fetal growth: ponderal index, head circumference/ abdominal circumference ratio, cephalization index and birth weight/ placenta weight ratio was collected. Cox proportional hazards regression models were used to estimate adjusted hazard ratios (aHR) and 95% confidence intervals (CI). All measurements were evaluated as gestational age and sex specific z-scores and in z-score percentile groups, adjusted for potential confounders, and st

SUBMITTER: Streja E 

PROVIDER: S-EPMC4431832 | biostudies-literature | 2015

REPOSITORIES: biostudies-literature