Factors associated with nocturnal hypoglycemia in at-risk adolescents and young adults with type 1 diabetes.

ABSTRACT:

Background

Hypoglycemia remains an impediment to good glycemic control, with nocturnal hypoglycemia being particularly dangerous. Information on major contributors to nocturnal hypoglycemia remains critical for understanding and mitigating risk.

Materials and methods

Continuous glucose monitoring (CGM) data for 855 nights were studied, generated by 45 subjects 15-45 years of age with hemoglobin A1c (HbA1c) levels of ≤8.0% who participated in a larger randomized study. Factors assessed for potential association with nocturnal hypoglycemia (CGM measurement of <60 mg/dL for ≥30 min) included bedtime blood glucose (BG), exercise intensity, bedtime snack, insulin on board, day of the week, previous daytime hypoglycemia, age, gender, HbA1c level, diabetes duration, daily basal ins

SUBMITTER: Wilson DM 

PROVIDER: S-EPMC4432491 | biostudies-literature | 2015 Jun

REPOSITORIES: biostudies-literature