ProtDCal: A program to compute general-purpose-numerical descriptors for sequences and 3D-structures of proteins.

ABSTRACT:

Background

The exponential growth of protein structural and sequence databases is enabling multifaceted approaches to understanding the long sought sequence-structure-function relationship. Advances in computation now make it possible to apply well-established data mining and pattern recognition techniques to these data to learn models that effectively relate structure and function. However, extracting meaningful numerical descriptors of protein sequence and structure is a key issue that requires an efficient and widely available solution.

Results

We here introduce ProtDCal, a new computational software suite capable of generating tens of thousands of features considering both sequence-based and 3D-structural descriptors. We demonstrate, by means of principle component analy

SUBMITTER: Ruiz-Blanco YB 

PROVIDER: S-EPMC4432771 | biostudies-literature | 2015 May

REPOSITORIES: biostudies-literature