Effect of the Probiotic Saccharomyces boulardii on Cholesterol and Lipoprotein Particles in Hypercholesterolemic Adults: A Single-Arm, Open-Label Pilot Study.

ABSTRACT:

Objectives

Elevated blood cholesterol levels are a major risk factor for coronary artery disease, the leading cause of death worldwide. Probiotics have been investigated as potential cholesterol-lowering therapies, but no previous studies have assessed the effect of the probiotic yeast Saccharomyces boulardii on cholesterol levels in human volunteers. The objective of this study was to examine the effect of S. boulardii on serum cholesterol and lipoprotein particles in hypercholesterolemic adults.

Design

This study was a single-arm, open-label pilot study.

Subjects

Twelve hypercholesterolemic participants were recruited into the study; one dropped out.

Intervention

Participants took 5.6×10(10) colony forming unit (CFU) encapsulated S. boulardii (Saccharomyces c

SUBMITTER: Ryan JJ 

PROVIDER: S-EPMC4432884 | biostudies-literature | 2015 May

REPOSITORIES: biostudies-literature