Transcriptional events co-regulated by hypoxia and cold stresses in Zebrafish larvae.

ABSTRACT:

Background

Hypoxia and temperature stress are two major adverse environmental conditions often encountered by fishes. The interaction between hypoxia and temperature stresses has been well documented and oxygen is considered to be the limiting factor for the thermal tolerance of fish. Although both high and low temperature stresses can impair the cardiovascular function and the cross-resistance between hypoxia and heat stress has been found, it is not clear whether hypoxia acclimation can protect fish from cold injury.

Results

Pre-acclimation of 96-hpf zebrafish larvae to mild hypoxia (5% O2) significantly improved their resistance to lethal hypoxia (2.5% O2) and increased the survival rate of zebrafish larvae after lethal cold (10°C) exposure. However, pre-acclimation of 96

SUBMITTER: Long Y 

PROVIDER: S-EPMC4432979 | biostudies-literature | 2015 May

REPOSITORIES: biostudies-literature