Literature-based discovery of salivary biomarkers for type 2 diabetes mellitus.

ABSTRACT: The alarming increase in type 2 diabetes mellitus (T2DM) underscores the need for efficient screening and preventive strategies. Select protein biomarker profiles emerge over time during T2DM development. Periodic evaluation of these markers will increase the predictive ability of diabetes risk scores. Noninvasive methods for frequent measurements of biomarkers are increasingly being investigated. Application of salivary diagnostics has gained importance with the establishment of significant similarities between the salivary and serum proteomes. The objective of this study is to identify T2DM-specific salivary biomarkers by literature-based discovery. A serial interrogation of the PubMed database was performed using MeSH terms of specific T2DM pathological processes in primary and secondar

SUBMITTER: Srinivasan M 

PROVIDER: S-EPMC4433061 | biostudies-literature | 2015

REPOSITORIES: biostudies-literature