A systematic review investigating the cumulative incidence of chronic kidney disease in young adults with impaired glucose tolerance.

ABSTRACT:

Background

It is known that risk of chronic kidney disease (CKD) is elevated in patients with diabetes mellitus but it is not clear whether the risk is also elevated with impaired glucose tolerance (IGT). If the risk is increased, it is not known if this is confined to people with IGT who progress to type 2 diabetes (T2DM). The purpose of this systematic review is to determine the relative risk of CKD in young adults (aged 18 to 40 years) with IGT (exposed group) compared to those without glycaemic abnormality (comparator group).

Methods/design

The following electronic databases will be systematically searched from inception to January 2015 for relevant studies: CINAHL, EMBASE, MEDLINE, PubMed, Cochrane libraries and grey literature. Two independent reviewers will screen sea

SUBMITTER: Jadhakhan F 

PROVIDER: S-EPMC4433064 | biostudies-literature | 2015 May

REPOSITORIES: biostudies-literature