Comparative transcriptomics uncovers alternative splicing changes and signatures of selection from maize improvement.

ABSTRACT:

Background

Alternative splicing (AS) is an important regulatory mechanism that greatly contributes to eukaryotic transcriptome diversity. A substantial amount of evidence has demonstrated that AS complexity is relevant to eukaryotic evolution, development, adaptation, and complexity. In this study, six teosinte and ten maize transcriptomes were sequenced to analyze AS changes and signatures of selection in maize domestication and improvement.

Results

In maize and teosinte, 13,593 highly conserved genes, including 12,030 multiexonic genes, were detected. By identifying AS isoforms from mutliexonic genes, we found that AS types were not significantly different between maize and teosinte. In addition, the two main AS types (intron retention and alternative acceptor) contributed

SUBMITTER: Huang J 

PROVIDER: S-EPMC4433066 | biostudies-literature | 2015 May

REPOSITORIES: biostudies-literature