Structural correlates of functional language dominance: a voxel-based morphometry study.

ABSTRACT:

Background and purpose

The goal of this study was to explore the structural correlates of functional language dominance by directly comparing the brain morphology of healthy subjects with left- and right-hemisphere language dominance.

Methods

Twenty participants were selected based on their language dominance from a cohort of subjects with known language lateralization. Structural differences between both groups were assessed by voxel-based morphometry, a technique that automatically identifies differences in the local gray matter volume between groups using high-resolution T1-weighted magnetic resonance images.

Results

The main findings can be summarized as follows: (1) Subjects with right-hemisphere language dominance had significantly larger gray matter volume in t

SUBMITTER: Jansen A 

PROVIDER: S-EPMC4433474 | biostudies-literature | 2010 Apr

REPOSITORIES: biostudies-literature