The role of body mass index in survival outcome for lymphoma patients: US intergroup experience.

ABSTRACT:

Background

The role of body mass index (BMI) in survival outcomes is controversial among lymphoma patients. We evaluated the association between BMI at study entry and failure-free survival (FFS) and overall survival (OS) in three phase III clinical trials, among patients with diffuse large B-cell lymphoma (DLBCL), follicular lymphoma (FL) and Hodgkin's lymphoma (HL).

Patients and methods

A total of 537, 730 and 282 patients with DLBCL, HL and FL were included in the analysis. Baseline patient and clinical characteristics, treatment received and clinical outcomes were compared across BMI categories.

Results

Among patients with DLBCL, HL and FL, the median age was 70, 33 and 56; 29%, 29% and 37% were obese and 38%, 27% and 37% were overweight, respectively. Age was sig

SUBMITTER: Hong F 

PROVIDER: S-EPMC4433526 | biostudies-literature | 2014 Mar

REPOSITORIES: biostudies-literature