Arvicanthis ansorgei, a Novel Model for the Study of Sleep and Waking in Diurnal Rodents.

ABSTRACT:

Study objectives

Sleep neurobiology studies use nocturnal species, mainly rats and mice. However, because their daily sleep/wake organization is inverted as compared to humans, a diurnal model for sleep studies is needed. To fill this gap, we phenotyped sleep and waking in Arvicanthis ansorgei, a diurnal rodent widely used for the study of circadian rhythms.

Design

Video-electroencephalogram (EEG), electromyogram (EMG), and electrooculogram (EOG) recordings.

Setting

Rodent sleep laboratory.

Participants

Fourteen male Arvicanthis ansorgei, aged 3 mo.

Interventions

12 h light (L):12 h dark (D) baseline condition, 24-h constant darkness, 6-h sleep deprivation.

Measurements and results

Wake and rapid eye movement (REM) sleep showed similar electrophys

SUBMITTER: Hubbard J 

PROVIDER: S-EPMC4434565 | biostudies-literature | 2015 Jun

REPOSITORIES: biostudies-literature