An integrated widefield imaging and spectroscopy system for contrast-enhanced, image-guided resection of tumors.

ABSTRACT:

Unlabelled

Tumor recurrence following surgery is a common and unresolved medical problem of great importance since surgery is the most widely used treatment for solid-mass tumors worldwide. A contributing factor to tumor recurrence is the presence of residual tumor remaining at or near the surgical site following surgery.

Goal

The primary objective of this study was to develop and evaluate an image-guided surgery system based on a near-infrared, handheld excitation source and spectrograph in combination with a widefield video imaging system.

Methods

This system was designed to detect the fluorescence of near-infrared contrast agents and, in particular, indocyanine green (ICG). The imaging system was evaluated for its optical performance and ability to detect the prese

SUBMITTER: Mohs AM 

PROVIDER: S-EPMC4435563 | biostudies-literature | 2015 May

REPOSITORIES: biostudies-literature