Biobehavioral factors mediate exercise effects on fatigue in breast cancer survivors.

ABSTRACT:

Purpose

This study aimed to examine mediators of fatigue response to an exercise intervention for breast cancer survivors in a pilot randomized controlled trial.

Methods

Postmenopausal breast cancer survivors (n = 46; ≤stage 2), off primary treatment, and reporting fatigue and/or sleep dysfunction were randomized to a 3-month exercise intervention (160 min·wk of moderate-intensity aerobic walking, twice weekly resistance training with resistance bands) or control group. Six discussion group sessions provided behavioral support to improve adherence. Fatigue, serum cytokines, accelerometer physical activity, cardiorespiratory fitness, sleep dysfunction, and psychosocial factors were assessed at baseline and 3 months.

Results

The exercise intervention effect sizes for fa

SUBMITTER: Rogers LQ 

PROVIDER: S-EPMC4435796 | biostudies-literature | 2014 Jun

REPOSITORIES: biostudies-literature