Recalibration and validation of the Charlson comorbidity index in Korean incident hemodialysis patients.

ABSTRACT:

Background

Weights assigned to comorbidities to predict mortality may vary based on the type of index disease and advances in the management of comorbidities. We aimed to develop a modified Charlson comorbidity index (CCI) in incident hemodialysis patients (mCCI-IHD), thereby improving risk stratification for mortality.

Methods

Data on 24,738 Koreans who received their first hemodialysis treatment between 2005 and 2008 were obtained from the Korean Health Insurance dataset. The mCCI-IHD score were calculated by summing up the weights which were assigned to individual comorbidities according to their relative prognostic significance determined by multivariate Cox proportional hazards model. The modified index was validated in an independent nationwide prospective cohort (n=1,

SUBMITTER: Park JY 

PROVIDER: S-EPMC4436150 | biostudies-literature | 2015

REPOSITORIES: biostudies-literature