Peroral endoscopic myotomy can improve esophageal motility in patients with achalasia from a large sample self-control research (66 patients).

ABSTRACT:

Background

Peroral endoscopic myotomy (POEM) as a new approach to achalasia attracts broad attention. The primary objective of this study was to evaluate the results with esophageal motility after POEM through the first large sample clinical research.

Patients and methods

We have a self-control research with all patients (205 in total) who underwent POEM from 2010 to 2014 at our Digestive Endoscopic Center, 66 patients of which underwent high resolution manometry (HRM) before and after POEM in our motility laboratory. Follow-ups last for 5.6 months on average. Outcome variables analyzed included upper esophageal sphincter pressure (UESP), upper esophageal sphincter residual pressure (UESRP), lower esophageal sphincter pressure (LESP), lower esophageal sphincter residual pres

SUBMITTER: Yao S 

PROVIDER: S-EPMC4436219 | biostudies-literature | 2015

REPOSITORIES: biostudies-literature