Cost-effectiveness of proton beam therapy for intraocular melanoma.

ABSTRACT:

Purpose

Proton beam therapy is a commonly accepted treatment for intraocular melanomas, but the literature is lacking in descriptions of patient preferences of clinical outcomes and economic impact. In addition, no economic evaluations have been published regarding the incremental cost-effectiveness of proton beam therapy compared with enucleation or plaque brachytherapy, typical alternative treatments. We, therefore, conducted a cost-utility analysis of these three approaches for the treatment of intraocular melanomas.

Materials and methods

A Markov model was constructed. Model parameters were identified from the published literature and publicly available data sources. Cost-effectiveness of each treatment was calculated in 2011 US Dollars per quality-adjusted life-year. In

SUBMITTER: Moriarty JP 

PROVIDER: S-EPMC4436277 | biostudies-literature | 2015

REPOSITORIES: biostudies-literature