Metabolic energy-based modelling explains product yielding in anaerobic mixed culture fermentations.

ABSTRACT: The fermentation of glucose using microbial mixed cultures is of great interest given its potential to convert wastes into valuable products at low cost, however, the difficulties associated with the control of the process still pose important challenges for its industrial implementation. A deeper understanding of the fermentation process involving metabolic and biochemical principles is very necessary to overcome these difficulties. In this work a novel metabolic energy based model is presented that accurately predicts for the first time the experimentally observed changes in product spectrum with pH. The model predicts the observed shift towards formate production at high pH, accompanied with ethanol and acetate production. Acetate (accompanied with a more reduced product) and butyrate a

SUBMITTER: Gonzalez-Cabaleiro R 

PROVIDER: S-EPMC4436308 | biostudies-literature | 2015

REPOSITORIES: biostudies-literature