Optimal feedback control successfully explains changes in neural modulations during experiments with brain-machine interfaces.

ABSTRACT: Recent experiments with brain-machine-interfaces (BMIs) indicate that the extent of neural modulations increased abruptly upon starting to operate the interface, and especially after the monkey stopped moving its hand. In contrast, neural modulations that are correlated with the kinematics of the movement remained relatively unchanged. Here we demonstrate that similar changes are produced by simulated neurons that encode the relevant signals generated by an optimal feedback controller during simulated BMI experiments. The optimal feedback controller relies on state estimation that integrates both visual and proprioceptive feedback with prior estimations from an internal model. The processing required for optimal state estimation and control were conducted in the state-space, and neural rec

SUBMITTER: Benyamini M 

PROVIDER: S-EPMC4436824 | biostudies-literature | 2015

REPOSITORIES: biostudies-literature