ImmuSort, a database on gene plasticity and electronic sorting for immune cells.

ABSTRACT: Gene expression is highly dynamic and plastic. We present a new immunological database, ImmuSort. Unlike other gene expression databases, ImmuSort provides a convenient way to view global differential gene expression data across thousands of experimental conditions in immune cells. It enables electronic sorting, which is a bioinformatics process to retrieve cell states associated with specific experimental conditions that are mainly based on gene expression intensity. A comparison of gene expression profiles reveals other applications, such as the evaluation of immune cell biomarkers and cell subsets, identification of cell specific and/or disease-associated genes or transcripts, comparison of gene expression in different transcript variants and probe set quality evaluation. A plasticity s

SUBMITTER: Wang P 

PROVIDER: S-EPMC4437374 | biostudies-literature | 2015 May

REPOSITORIES: biostudies-literature