Altered organization of face-processing networks in temporal lobe epilepsy.

ABSTRACT:

Objective

Deficits in social cognition are common and significant in people with temporal lobe epilepsy (TLE), but the functional and structural underpinnings remain unclear. The present study investigated how the side of seizure focus impacts face-processing networks in temporal lobe epilepsy.

Methods

We used functional magnetic resonance imaging (fMRI) of a face-processing paradigm to identify face-responsive regions in 24 individuals with unilateral temporal lobe epilepsy (left = 15; right = 9) and 19 healthy controls. fMRI signals of face-responsive regions ipsilateral and contralateral to the side of seizure onset were delineated in TLE and compared to the healthy controls with right and left sides combined. Diffusion tensor images were acquired to investigate structura

SUBMITTER: Riley JD 

PROVIDER: S-EPMC4437862 | biostudies-literature | 2015 May

REPOSITORIES: biostudies-literature