Nanoparticle-nanoparticle interactions in biological media by atomic force microscopy.

ABSTRACT: Particle-particle interactions in physiological media are important determinants for nanoparticle fate and transport. Herein, such interactions are assessed by a novel atomic force microscopy (AFM)-based platform. Industry-relevant CeO2, Fe2O3, and SiO2 nanoparticles of various diameters were made by the flame spray pyrolysis (FSP)-based Harvard Versatile Engineering Nanomaterials Generation System (Harvard VENGES). The nanoparticles were fully characterized structurally and morphologically, and their properties in water and biological media were also assessed. The nanoparticles were attached on AFM tips and deposited on Si substrates to measure particle-particle interactions. The corresponding force was measured in air, water, and biological media that are widely used in toxicological stu

SUBMITTER: Pyrgiotakis G 

PROVIDER: S-EPMC4438084 | biostudies-literature | 2013 Sep

REPOSITORIES: biostudies-literature